At the end of the fifteenth century, simplified versions of medical charts featuring an image of the "Zodiac Man" began to appear in Books of Hours. The Lessing J. Rosenwald Collection in the Rare Book and Special Collections Division contains many examples of these printed editions, one of which uses a skeleton in place of the Zodiac Man.
Printed in Basel in 1543, Andreas Vesalius' De Humani Corporis Fabrica is considered to be the first "modern" medical book that emphasizes clinical observation over a dependence on ancient texts. The Library of Congress has recently digitized its copy of De Fabrica, which was part of the generous gift of Lessing J. Rosenwald to the nation.
The Library of Congress has several important works by the printmaker, painter, and art theorist, Albrecht Dürer (1471-1528), including his famous engraving, Melencolia I (1514), and his Treatise on Measurement (1525).
Gregor Reisch's (c.1470-1525) encyclopedic textbook, Margarita Philosophica (Philosophical Pearl) contains a woodcut that speaks to the process of education in the sixteenth century.